GB88 is a potent PAR2 antagonist that is orally bioavailable. A

gb88GB88 is a PAR2 receptor antagonist [1]. It inhibits the proinflammatory and pronociceptive actions of trypsin, cathepsinSuen JY, et al. Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110). Br J Pharmacol. 2012 Mar;165(5):1413-23. [Content Brief]